Sure Fetal Bovine Sera, Heat Inactivated, Sterile Filtered, Australia

Fetal bovine serum (FBS) is a ubiquitously used essential supplement in cell culture media. FBS is a cocktail of proteins, vitamins, carbohydrates, lipids, hormones, growth factors, minerals and trace elements and is used as an universal growth supplement effective for most types of human and animal (including insect) cells. The major functions of serum in culture media are to provide: i. Hormonal factors stimulating cell growth and proliferation and promoting differentiated functions. ii. Transport proteins carrying hormones (e.g. transcortin), minerals and trace elements (e.g. transferrin) and lipids (e.g. lipoproteins) iii. Attachment and spreading factors, acting as germination points for cell attachment. iv. Stabilizing and detoxifying factors needed to maintain pH or to inhibit proteases either directly, such as αantitrypsin or α2-macroglobulin, or indirectly, by acting as an unspecific sink for proteases and other (toxic) molecules. RM10679 is heat inactivated fetal bovine serum. Heat inactivation is done to destroy heat labile components such as complement that can lead to complement mediated cell lysis. Complement proteins, antibodies and enzymes present in the serum are inactivated by heat inactivation. This fetal bovine serum collected from AQIS (Australian Quarantine and Inspection Service) approved abattoirs in Australia. Australia is considered to be free of BSE and FMD and belongs to GBR 1 category. Australian-origin serum is most commonly used in the production of many human and animal biopharmaceuticals and is proven to support the needs of industrial biopharmaceutical manufacturers.