Kanamycin acid sulphate

SKU:
TC636M
CAS Number : 64013-70-3
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Product Identifier

Product Code TC636M
Product Description Kanamycin acid sulphate
CAS No. 64013-70-3

Technical Specification

Appearance (BP, IP) A white or almost white hygroscopic powder
Solubility (BP) Soluble in about 1 part of water, practically insoluble in acetone and in alcohol
Solubility (IP) Freely soluble in water, practically insoluble in ethanol (95%) in acetone, in chloroform and in ether
Identification A : TLC (IP, BP) The principal spot in the chromatogram obtained with the test solution corresponds to that in the chromatogram obtained with reference solution (a). The test is not valid unless the chromatogram obtained with reference solution (b) shows three clearly separated spots.
Identification B : Melting point (IP, BP) The melting point of the crystals, after washing with 20 ml of water and drying at 105°C, is about 235°C with decomposition
Identification C : (IP, BP) A violet colour is produced
Identification D: Sulphates (IP, BP) Complies
pH (1% in water at 25°C) : (IP, BP) 5.50-7.50
Specific optical rotation : (IP, BP) +103.00 to +115.00° (1% in water at 20±0.5°C)
Kanamycin B : (IP, BP) Any spot corresponding to kanamycin B in the chromatogram obtained with the test solution is not more intense than the spot in the chromatogram obtained with the reference solution
Sulfate (IP, BP) 23.00 - 26.00%
Sulfated ash (IP, BP) < = 0.50%
Loss on drying (IP, BP) <= 5.00% (at 60°C at a pressure not exceeding 0.7 kPa for 3 h)
Potency: (IP) >= 650 Units/mg
Potency: (BP) >= 670 IU/mg
Bacterial endotoxins (IP) < = 0.67 EU/mg of kanamycin
Sterility (IP) Complies

Storage and Shelf Life

Store below 30°C away from bright light.
Shelf life 36 months.
Use before expiry date given on the product label.
CAS Number : 64013-70-3
More Information
Product Name Kanamycin acid sulphate
SKU TC636M
CAS No 64013-70-3
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