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Product Identifier
| CAS No. |
9005-64-5 |
| Synonym |
Tween® 20 |
Technical Specification
| Appearance (USP) |
Lemon to amber coloured liquid |
| Appearance (EP, BP) |
Oily, yellow or brownish-yellow, clear or slightly opalescent liquid |
| Appearance (IP) |
A clear or slightly opalescent, oily, yellowish or brownish yellow liquid |
| Solubility (USP) |
Soluble in water, in alcohol, in ethyl acetate; in methanol and in dioxane; insoluble in mineral oil |
| Solubility (EP, BP) |
Soluble in water, in anhydrous ethanol, in ethyl acetate and in methanol. Practically insoluble in fatty oils and in liquid paraffin. |
| Solubility (IP) |
Miscible with water, with ethanol, with ethyl acetate and with methanol; practically insoluble in fixed oils and in liquid paraffin |
| pH (5% in water) : (IP) |
5.0 - 7.0 |
| Identification A : FTIR (USP, EP, BP, IP) |
Matches with the standard pattern |
| Identification B : Hydroxyl value (EP, BP) |
96.0 - 108.0 |
| Identification B: (IP) |
A blue colour is produced |
| Identification B: Composition of fatty acid, GC (USP) |
Meets the requirements |
| Identification C : Saponification value (EP, BP) |
40.0 - 50.0 |
| Identification D: Composition of fatty acids, GC (EP, BP) |
Complies |
| Identification Test E (EP, BP) |
The solution becomes blue |
| Acid value (USP, EP, BP, IP) |
<= 2.0 |
| Hydroxyl value (USP, EP, BP, IP) |
96 - 108 |
| Peroxide value (USP, EP, BP) |
<= 10.0 |
| Iodine value (IP) |
<= 5.0 |
| Saponification value (USP, EP, BP, IP) |
40.0 - 50.0 |
| Relative density (EP, BP) |
about 1.10 |
| Reducing impurities : (IP) |
NMT 2.0 mL of 0.01M ceric ammonium sulphate is required |
| viscosity (EP, BP) |
~400 mPa.s at 25°C |
| Heavy metals (IP) |
<= 0.0010% |
| System suitability, limit of ethylene oxide : Resolution (USP) |
>= 2.0 |
| Limit of ethylene oxide, GC-HS (USP, EP, BP) |
<= 0.0001% |
| Limit of Dioxane, GC-HS (USP, EP, BP) |
<= 0.0010% |
| Residue on ignition (USP) |
<= 0.25% |
| Total ash (EP, BP) |
<= 0.25% |
| Sulphted ash (IP) |
<= 0.2% |
| Water (USP, EP, BP, IP) |
<= 3.0% |
| System suitability 1, composition of fatty acids, GC: Resolution (USP) |
>= 1.5, between methyl stearate and methyl oleate |
| System suitability 2, composition of fatty acids, GC: RSD (USP) |
<= 6.0%, peak area responses for the palmitate and stearate peaks |
| System suitability 3, composition of fatty acids, GC: RSD (USP) |
<= 1.0%, peak area response ratio for the palmitate and stearate peaks |
| System suitability 4, composition of fatty acids, GC: Resolution (EP, BP) |
>= 4.0, between the peaks due to methyl caprylate and methyl decanoate |
| System suitability 5, composition of fatty acids, GC: Theoretical plates (EP, BP) |
>= 15,000 for the peak due to methyl decanoate |
| Composition of fatty acids 1, GC : Caproic acid (USP, EP, BP) |
<= 1.0% |
| Composition of fatty acids 2, GC : Caprylic acid (USP, EP, BP) |
<= 10.0% |
| Composition of fatty acids 3, GC : Capric acid (USP, EP, BP) |
<= 10.0% |
| Composition of fatty acids 4, GC : lauric acid (USP, EP, BP) |
40.0 - 60.0% |
| Composition of fatty acids 5, GC : myristic acid (USP, EP, BP) |
14.0 - 25.0% |
| Composition of fatty acids 6, GC : palmitic acid (USP, EP, BP) |
7.0 - 15.0% |
| Composition of fatty acids 7, GC : stearic acid (USP) |
<= 11.0% |
| Composition of fatty acids 8, GC : stearic acid (EP, BP) |
<= 7.0% |
| Composition of fatty acids 9, GC : oleic acid (USP, EP, BP) |
<= 11.0% |
| Composition of fatty acids 10, GC : linoleic acid (USP, EP, BP) |
<= 3.0% |
Storage and Shelf Life
| Storage |
Store below 30°C away from bright light. |
| Shelf life |
48 months. Use before expiry date given on the product label. |
CAS Number :
9005-64-5
Synonym :
Tween®20
More Information
| Product Name |
Polysorbate 20 |
| SKU |
TC287M |
| CAS No |
9005-64-5 |
| EC No. |
500-018-3 |
| Synonym |
Tween®20 |