Plot No. C40, Road No. 21Y, MIDC, Wagle Industrial Estate, Thane(W)-400604, MH, India
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L-Histidine
SKU:
TC076M
CAS Number :
71-00-1
Molecular Formula :
C₆H₉N₃O₂
Availability: In stock
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$154.70
Product Identifier
| Product Name | L-Histidine (From non-animal source) |
|---|---|
| Product Code | TC076M |
| Molecular weight | 155.15 |
| Molecular formula | C6H9N3O2 |
| CAS No. | 71-00-1 |
Technical Specification
| Appearance (USP) | White, odourless crystals |
|---|---|
| Appearance (EP, BP) | White or almost white, crystalline powder or colourless crystals |
| Appearance (JP) | White, crystals or crystalline powder |
| Solubility (USP) | Soluble in water; very slightly soluble in alcohol; insoluble in ether |
| Solubility (EP, BP) | Soluble in water, very slightly soluble in ethanol (96%) |
| Solubility (JP) | Freely soluble in formic acid, and soluble in water and practically insoluble in ethanol (99.5%), It dissolves in 6 mol/L HCI TS |
| pH (2% in water) : (JP, USP) | 7.00-8.50 |
| Identification: FTIR (JP) | Matches with the standard pattern |
| Identification A : FTIR (USP) | Matches with the standard pattern |
| Identification A : Specific rotation (dried substance) (EP, BP) | +11.40° to +12.40° (dissolve 2.75 gm in 12 mL of hydrochloric acid R1 and dilute to 25 mL with water at 20 ± 0.5°C, dried basis) |
| Identification B: FTIR (EР, ВР) | Matches with the standard pattern |
| Identification C : TLC (EP, BP) | The principal spot in the chromatogram obtained with test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution |
| Identification D (EP, BP) | An orange-red colour develops |
| Appearance of the solution (EP, BP) | 5% solution in water is clear and not more intensely coloured than reference solution BY7 |
| Clarity and color of solution (JP) | 2% solution in water is clear and colourless |
| Chloride (USP) | <= 0.05% |
| Chloride (EP, ВР) | <= 0.02% |
| Chloride (JP) | <= 0.021% |
| Ammonium (JP) | <= 0.02% |
| Ammonium: Amino acid analysis (EP, BP) | <= 0.02% |
| Heavy metals (JP) | <= 0.001% |
| Iron (USP) | <= 0.003% |
| Iron (JP, EP, BP) | <= 0.001% |
| Sulphate (JP) | <= 0.028% |
| Sulphate (USP, EP, BP) | <= 0.03% |
| Optical rotation (JP) | +11.80° to +12.80° (c=11% in 6 mol/L hydrochloric acid TS at 20°C, dried basis) |
| Specific rotation (EP, BP) | +11.40° to +12.40° (dissolve 2.75 gm in 12 mL of hydrochloric acid R1 and dilute to 25 mL with water at 20 ±0.5°C, dried basis) |
| Specific rotation (USP) | +12.60° to +14.00° (c=11% in 6N hydrochloric acid at 25°C) |
| Loss on drying (JP) | <= 0.30% (at 105°C, 3 hr) |
| Loss on drying (USP) | <= 0.20% (at 105°C, 3 hr) |
| Loss on drying (BP, EP) | <= 0.50% (at 105°C, till constant weight) |
| Residue on ignition (JP) | <= 0.10% |
| Residue on ignition (USP) | <= 0.40% |
| Sulfated ash (EP, BP) | <= 0.10% |
| Related substances : TLC (JP) | The spot other than the principal spot obtained from the sample solution is not more intense than the spot obtained from the standard solution. |
| Ninhydrin-positive substances : system suitability: Amino acid analysis: resolution (EP, BP) | min.1.5 between the peaks due to isoleucine and leucine |
| Ninhydrin-positive substances : any ninhydrin-positive substance, for each impurity : Amino acid analysis (EP,BP) | <= 0.20% |
| Ninhydrin-positive substances : Total impurity : Amino acid analysis (EP, ВР) | <= 0.50% |
| Related componds, TLC : (USP) | Any secondary spot of the sample solution is not larger or more intense than the principal spot of the standard solution |
| Related compounds, individual impurities : TLC (USP) | <= 0.50% |
| Related compounds, total impurities : TLC (USP) | <= 2.0% |
| Assay (NT, dried basis) : (USP) | 98.50-101.50% |
| Assay (HCl Titration, dried substance) : (EP, BP) | 98.50-101.00% |
| Assay (NT, dried basis) : (JP) | 99.00-101.00% |
| Bacterial endotoxin | <= 6 EU/g |
| Storage | Store below 30°C away from bright light. |
| Shelf life | 48 months. |
| Usage | Use before expiry date given on the product label. |
CAS Number :
71-00-1
Molecular Formula :
C₆H₉N₃O₂
| Product Name | L-Histidine |
|---|---|
| SKU | TC076M |
| CAS No | 71-00-1 |
| EC No. | 200-745-3 |
| Molecular formula | C₆H₉N₃O₂ |
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