Plot No. C40, Road No. 21Y, MIDC, Wagle Industrial Estate, Thane(W)-400604, MH, India
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L-Arginine monohydrochloride
SKU:
TC053M
CAS Number :
1119-34-2
Molecular Formula :
C₆H₁₄N₄O₂.HCl
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Product Information
| Product Code | TC053M |
|---|---|
| Molecular weight | 210.66 |
| Molecular formula | C6H14N4O2.HCl |
| CAS No. | 1119-34-2 |
Quality Control
| Appearance (EP, BP) | White or almost white, crystalline powder or colorless crystals |
|---|---|
| Appearance (JP, USP) | White crystals or crystalline powder. |
| Solubility (EP, BP) | Freely soluble in water, very slightly soluble in ethanol (96%) |
| Solubility (USP) | Freely soluble in water |
| Solubility (JP) | Freely soluble in water and in formic acid and very slightly soluble in ethanol (95%) |
| Appearance of solution (EP, BP) | 5% solution in water is clear and not more intensely colored than reference solution BY6 |
| Clarity and colour of solution (JP) | The solution is clear and colorless |
| pH (10% in water at 25°C) : (JP) | 4.70-6.20 |
| Identification 1: FTIR (JP) | Matches with the standard pattern |
| Identification A : Specific rotation (EP, BP) | +21.00° to +23.50° (c = 8% in HCl R1 at 20 ± 0.5°C, dried substances) |
| Identification A : FTIR (USP) | Matches with the standard pattern |
| Identification 2 : Chloride (JP) | Complies |
| Identification B : FTIR (EP, BP) | Matches with the standard pattern |
| Identification C : TLC (EP, EP) | The principal spot in the chromatogram obtained with test solution is similar in position, colour and size to the principal spots in the chromatogram obtained with the reference solution |
| Identification D : (EP, BP) | A red colour develops |
| Identification E: Chloride (EP, BP) | It gives reaction (a) of chloride |
| Specific rotation (EP, BP) | +21.00° to +23.50° (c = 8% in HCl R1 at 20 ± 0.5°C, dried substances) |
| Specific rotation (USP) | +21.40° to +23.60°(c= 8% in 6N HCl at 20°C) |
| Specific rotation (JP) | +21.50° to +23.50°(c= 8% in 6M HCl at 20°C) |
| Ninhydrin-positive substances (Amino acid analysis) : System suitability : Resolution (EP, BP) | >= 1.5 between the peaks due to isoleucine and leucine |
| Ninhydrin-positive substances 1 (Amino acid analysis) : For each impurity (EP, BP) | <= 0.20% |
| Ninhydrin-positive substances 2 (Amino acid analysis) : Total impurity (EP, BP) | <= 0.50% |
| Chromatographic purity, TLC : System suitability (USP) | Any secondary spot from the sample solution is not larger or more intense than the principal spot from the standard solution |
| Chromatographic purity 1 (TLC) : Individual impurities (USP) | <= 0.50% |
| Chromatographic purity 2 (TLC) : Total impurities (USP) | <= 2.00% |
| Related substances, TLC : (JP) | The spots other than the principal spot from the sample solution are not more intense than the spot from the standard solution. |
| Sulfate (EP, BP) | <= 0.03% |
| Heavy metals : (JP) | <= 0.0020% |
| Sulfate (USP) | <= 0.03% |
| Sulfate (JP) | <= 0.028% |
| Ammonium (Amino acid analysis) : (BP, EP) | Complies |
| Ammonium (JP) | <= 0.02% |
| Arsenic (JP) | <= 0.0002% |
| Iron (EP, BP) | <= 0.0010% |
| Loss on drying (at 105°C, 2 hr) (EP, BP) | <= 0.50% |
| Loss on drying (at 105°C, 3 hr) : (JP) | <= 0.20% |
| Loss on drying (at 105°C, 2 hr) : (USP) | <= 0.20% |
| Residue on ignition (USP, JP) | <= 0.10% |
| Sulfated ash (EP, BP) | <= 0.10% |
| Chloride content : AT (USP) | 16.50-17.10% |
| Assay (NT, dried substance) (EP, BP) | 98.50 - 101.00% |
| Assay (NT, on dried basis) : (USP) | 98.50 - 101.50% |
| Assay (NT, on dried basis) : (JP) | >= 98.50% |
Storage and Shelf Life
| Storage Condition | Store below 30°C away from bright light. |
|---|---|
| Shelf life | 48 months. |
| Use Instruction | Use before expiry date given on the product label. |
CAS Number :
1119-34-2
Molecular Formula :
C₆H₁₄N₄O₂.HCl
| Product Name | L-Arginine monohydrochloride |
|---|---|
| SKU | TC053M |
| CAS No | 1119-34-2 |
| EC No. | 214-275-1 |
| Molecular formula | C₆H₁₄N₄O₂.HCl |
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