Hi-PCR® Carbapenemase Gene (Multiplex) Probe PCR Kit is designed to detect the specific regions of the genes encoding the carbapenemase enzymes, namely, NDM, KPC, IMP, VIM, OXA-51, OXA-23, OXA-48 and OXA-58 along with Internal control.
The emergence and spread of carbapenem hydrolyzing ?-lactamases amongst Gram negative bacteria over the past decade represent a serious issue in the hospital and community environments. These enzymes hydrolyze almost all ?-lactam antimicrobial and often are also resistant to commercially available ?-lactamase inhibitors. a major clinical concern and rapidly identifying the organisms carrying these genes might be the best way we have to reduce or prevent this problem. Various types of carbapenemases are very commonly encountered in Enterobactericeae and other Gram-negative bacteria. Hi-PCR® Carbapenemase Gene (Multiplex) Probe PCR Kit is designed to detect the specific regions of the genes encoding the carbapenemase enzymes, namely, NDM, KPC, IMP, VIM, OXA-51, OXA-23, OXA-48 and OXA-58 along with Internal control.