Hi-PCR® Beta-Thalassemia Semi-Q PCR Kit (Uniplex) targets specific regions of the beta globin gene to identify allelic variations. This PCR Kit enables HBB Mutation Analysis for Genetic Testing and Hemoglobinopathy Hereditary Disorder Screening. This kit is a qualitative in vitro diagnostic tool for detecting five common mutations responsible for beta-thalassemia in clinical samples. It can identify both heterozygous (carrier) and homozygous (affected) genotypes. It is suitable for diagnostic screening, genetic counseling, mutation profiling, and prenatal diagnosis.
Thalassemia is a group of genetic disorders characterized by quantitative defects in globin chain synthesis with subsequent absence or decrease of hemoglobin production leading to variable degrees of microcytic anemia; it is commonly found in people of Mediterranean, African, Middle Eastern, Indian, Chinese or Southeast Asian origin. HiMedia's Hi-PCR® Beta-Thalassemia Semi-Q PCR Kit (Uniplex) is a qualitative conventional PCR kit which contains 4 different genes to detect mutant and normal beta Thalassemia samples. This kit is designed to identify homozygous and heterozygous samples with beta thalassemia mutations. The kit also contains internal control to overcome the possibility that the absence of product could be due to failure of PCR.