Hi-PCR® Monkeypox Virus Multiplex probe PCR kit

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SKU:
MBPCR269
The Hi‐PCR® Monkeypox Virus Multiplex Probe PCR Kit is a ready‐to‐use real‐time PCR system designed for accurate detection of Monkeypox virus and orthopoxvirus DNA. It utilizes hydrolysis probes—short oligonucleotides with a fluorescent dye and a quencher dye. During amplification, the probe is cleaved by DNA polymerase, separating the dyes and increasing fluorescence, which is monitored in real‐time for precise detection. This kit features primers and probes targeting specific regions of the Monkeypox virus(MPXV) and a generic orthopoxvirus gene (POPV), along with a human internal control (IC) to ensure test reliability. Detection is facilitated through three fluorescent channels: FAM for MPXV, JOE for POPV, and Texas Red for internal control.


By mid‐2023, the World Health Organization (WHO) reported that over 80,000 cases had been confirmed globally, with a substantial number of cases occurring in previously non‐endemic regions. As of early September 2024, the WHO reported a total of approximately 95,000 confirmed cases worldwide since the beginning of the 2022 outbreak. The most affected regions include the Americas and Europe, with a notable increase in cases reported in the United States, Brazil, and several European countries. The outbreak has led to several fatalities, though the majority of cases have been mild or moderate. Effective surveillance, precise diagnosis, and prompt management are essential for controlling monkeypox outbreaks. Recent advancements in molecular diagnostics have greatly enhanced the detection and management of this virus. Real‐time PCR assays, which are considered the gold standard for rapid diagnosis, have seen innovations such as multiplex assays that can distinguish monkeypox from other orthopoxviruses. The Hi‐PCR® Monkeypox Virus Multiplex Probe PCR Kit exemplifies these advancements, offering a streamlined approach for rapid diagnosis of monkeypox in a single tube.
NOTE: Hi‐PCR® Monkeypox Virus Multiplex Probe PCR Kit is for in‐vitro use only.
More Information
Product Name Hi-PCR® Monkeypox Virus Multiplex probe PCR kit
SKU MBPCR269
Customized Product Available No
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