Adult Bovine Sera, Sterile Filtered, Heat Inactivated

Adult bovine serum (ABS) is collected from adult cows brought to slaughter. The serum is separated from the blood of adult cows more than 12 months old by mechanical defibrination process. It contains more immunoglobulins than FBS and has double the protein content than FBS. ABS has low hemoglobin content. ABS is commonly used to supplement basal cell culture media to boost the growth and proliferation of multiple cell types. ABS is not recommended for hybridomas, embryonic stem cells and other fastidious cell types. RM10913 is heat inactivated adult bovine serum. Heat inactivation is done to destroy heat labile components such as complement that can lead to complement mediated cell lysis. Complement proteins, antibodies and enzymes present in the serum are inactivated by heat inactivation.