Plot No. C40, Road No. 21Y, MIDC, Wagle Industrial Estate, Thane(W)-400604, MH, India
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Citric acid monohydrate
SKU:
TC454M
CAS Number :
5949-29-1
Molecular Formula :
C₆H₈O₇.H₂O
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Chemicals Meeting Pharmacopoeial Testing Specifications#ff0000
Product Identifier
| Product Code | TC454M |
|---|
Product Description
| Molecular weight | 210.14 |
|---|---|
| Molecular formula | C6H8O7.H2O |
| CAS No. | 5949-29-1 |
Quality Control
| Appearance (USP) | Colorless, translucent crystals, or white granular to fine crystalline powder. |
|---|---|
| Appearance (JP) | Colorless crystals, white granules or crystalline powder. |
| Appearance (EP, BP) | White or almost white, crystalline powder, colourless crystals or granules. |
| Appearance (IP) | Colourless crystals or a white crystalline powder, slightly efflorescent in warm, dry air |
| Solubility (USP) | Very soluble in water, freely soluble in alcohol, very slightly soluble in ether |
| Solubility (JP) | Very soluble in water, and freely soluble in ethanol (99.5%) |
| Solubility (EP, BP) | Very soluble in water, freely soluble in ethanol (96%) |
| Solubility (IP) | Very soluble in water; freely soluble in ethanol (95%); sparingly soluble in ether |
| Identification : FTIR (JP) | Matches with the standard pattern (dry the substance at 105°C for 2h) |
| Identification A (EP, BP) | 10% solution in water is strongly acidic |
| Identification A : FTIR (USP, IP) | Matches with the standard pattern (dry the substance at 105°C for 2 h) |
| Identification B : FTIR (EP, BP) | Matches with the standard pattern (dry the substance at 105 ±2°C for 2h) |
| Identification B (IP) | Reaction (A) for citrates |
| Identification C (EP, BP) | A red colour develops |
| Identification C (IP) | 10% solution in water is strongly acidic |
| Identification D (EP, BP) | A white precipitate is formed. |
| Identification E: Water (EP, BP) | 7.50 - 9.00% |
| Appearance of solution (EP, BP) | The solution is clear and colourless or not more intensely coloured than reference solution Y7, BY7 or GY7 |
| Appearance of solution (IP) | 20% w/v solution in water is clear and not more intensely coloured than reference solution YS7, BYS7 or GYS7 |
| Clarity of solution (USP) | The sample solution shows the same clarity as that of water or its opalescence is not more pronounced than standard suspension A |
| Colour of solution (USP) | The sample solution is not more intensely coloured than standard solution A, B and C |
| Clarity and color of solution (JP) | The solution is clear and colorless or has no more color than the control solutions (1), (2) or (3). |
| Readily carbonisable substances (EP, BP) | The solution is not more intensely coloured than a mixture of 1 mL of red primary solution and 9 mL of yellow primary solution |
| Readily carbonisable substances (USP) | The colour of the acid is nor darker than that of a similar volume of matching fluid K |
| Readily carbonisable substances (JP) | The solution is not more colored than the matching fluid. |
| Readily carbonisable substances (IP) | Any colour produced is not more intense than that of a mixture of 1.0 ml of CCS and 9.0 ml of FCS |
| Oxalic acid (IP) | Any pink colour produced is not more intense than that produced by carrying out the test using 0.2 mg of oxalic acid dissolved in 4 ml of water |
| Oxalic acid (EP, BP, USP, JP) | <= 0.036% |
| Sulfates (JP, BP, EP, USP, IP) | <= 0.015% |
| Iron (IP) | <= 0.005% |
| Chloride (IP) | <= 0.005% |
| Barium (IP) | Any opalescence produced is not more intense than that of a mixture of 5 ml of solution A and 5 ml of distilled water |
| Arsenic (IP) | <= 0.0001% |
| Calcium (IP) | <= 0.02% |
| Aluminium (EP, BP, USP) | <= 0.00002% |
| Heavy metals (JP, IP) | <= 0.0010% |
| Water (EP, BP, USP, JP, IP) | 7.50 - 9.00% |
| Sulfated ash (EP, BP, IP) | <= 0.10% |
| Residue on ignition (JP, USP) | <= 0.10% |
| Assay (NaOH Titration, on anhydrous basis) : (USP, EP, BP, JP) | 99.50 - 100.50% |
| Assay (NaOH Titration, on anhydrous basis) : IP | 99.00 - 101.00% |
| Bacterial endotoxins test (USP) | Complies |
| Bacterial endotoxins (EP, BP) | <= 0.50 IU/mg |
Storage and Shelf Life
| Store below | 30°C. |
|---|---|
| Shelf life | 48 months. |
| Use before | expiry date given on the product label. |
CAS Number :
5949-29-1
Molecular Formula :
C₆H₈O₇.H₂O
| Product Name | Citric acid monohydrate |
|---|---|
| SKU | TC454M |
| CAS No | 5949-29-1 |
| EC No. | 201-069-1 |
| Molecular formula | C₆H₈O₇.H₂O |
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