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Chemicals Meeting Pharmacopoeial Testing Specifications#ff0000
Product Information
| Product Code |
TC450M |
| Molecular Formula |
C₂H₆OS |
| Molecular Weight |
78.13 |
| CAS No. |
67-68-5 |
| Synonym |
Dimethyl sulfoxide |
Quality Control
| Appearance (EP, BP) |
Colourless liquid or colourless crystals, hygroscopic |
| Appearance (USP) |
Clear colorless hygroscopic liquid |
| Solubility (EP, BP) |
Miscible with water and with ethanol (96%) |
| Solubility (USP) |
Soluble in water. Practically insoluble in acetone, in alcohol, in benzene, in chloroform and in ether |
| Identification A : Relative density (EP, BP) |
1.100 - 1.104 g/mL |
| Identification A : FTIR (USP) |
Matches with the standard pattern |
| Identification B : Refractive index (EP, BP) |
1.478 - 1.480 |
| Identification B (USP) |
A deep violet, crystalline solid is obtained, and it is soluble in chloroform, yielding a red solution. |
| Identification C : FTIR (EP, BP) |
Matches with the standard pattern |
| Identification D (EP, BP) |
The colour changes to greenish-yellow |
| Acidity (EP, BP, USP) |
<= 5.0 mL of 0.01M NaOH is required to produce a pink colour |
| Relative density (EP, BP) |
1.100 - 1.104 |
| Refractive index (EP, BP) |
1.478 - 1.480 |
| Refractive index (USP) |
1.4755 - 1.4775 |
| Freezing point (EP, BP) |
min. 18.3°C |
| Specific gravity (USP) |
1.095 - 1.101 |
| Absorbance 1 (EP, BP) |
<= 0.30 (at 275 nm, use water as the compensation liquid) |
| Absorbance 2 (EP, BP) |
<= 0.20 (at 285nm and 295nm, use water as the compensation liquid) |
| Absorbance 3 (EP, BP, USP) |
The substance shows no absorption maximum between 270 - 350 nm |
| Absorbance (USP) |
<= 0.20 (at 275 nm, use water as the blank) |
| Absorbance ratio 1 (USP) |
<= 0.65 (at A285/A275) |
| Absorbance ratio 2 (USP) |
<= 0.45 (at A295/A275) |
| Water (USP) |
<= 0.10% |
| Limit of nonvolatile residue (USP) |
<= 0.01% |
| Water (EP, BP) |
<= 0.20% |
| Related substances 1 : (system suitability, GC) : Resolution (EP, BP) |
>= 3.00, between the peaks due to dimethyl sulfoxide and dimethyl sulfone |
| Related substances 2 : (system suitability, GC) : Resolution (USP) |
>= 5.00, between the peaks dimethyl sulfone and dibenzyl |
| Related substances 3 : (system suitability, GC) : Theoretical plates (USP) |
>= 1000, for dimethyl sulfoxide peak |
| Related substances (GC) : Total impurities (USP, EP, BP) |
<= 0.10% |
| Assay (GC, on anhydrous basis) : (USP) |
min. 99.90% |
Storage and Shelf Life
| Store |
Store below 30°C away from bright light. |
| Shelf life |
48 months. |
| Use |
Use before expiry date given on the product label. |
CAS Number :
67-68-5
Synonym :
Dimethyl sulfoxide
Molecular Formula :
C₂H₆OS
More Information
| Product Name |
CryoXL™DMSO |
| SKU |
TC450M |
| CAS No |
67-68-5 |
| EC No. |
200-664-3 |
| Molecular formula |
C₂H₆OS |
| Synonym |
Dimethyl sulfoxide |