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Chemicals Meeting Pharmacopoeial Testing Specifications#ff0000
Product Description
| Molecular Formula |
C₆H₈O₇ |
| Molecular Weight |
192.12 |
| CAS |
77-92-9 |
Quality Control
| Appearance (USP) |
Colorless, translucent crystals, or white granular to fine crystalline powder. |
| Appearance (JP) |
Colorless crystals, white granules or crystalline powder. |
| Appearance (EP, BP) |
White or almost white, crystalline powder, colourless crystals or granules. |
| Appearance (IP) |
Colourless crystals or a white powder; slightly hygroscopic in moist air |
| Solubility (JP) |
Very soluble in water, and freely soluble in ethanol (99.5%) |
| Solubility (EP, BP) |
Very soluble in water, freely soluble in ethanol (96%) |
| Solubility (IP) |
Very soluble in water, freely soluble in ethanol (95%), sparingly soluble in ether |
| Solubility (USP) |
Very soluble in water, freely soluble in alcohol, very slightly soluble in ether |
| Identification : FTIR (JP) |
Matches with the standard pattern (dry the substance at 105°C for 2h) |
| Identification A (EP, BP) |
The solution is strongly acidic |
| Identification A : FTIR (USP, IP) |
Matches with the standard pattern (dry the substance at 105°C for 2 h) |
| Identification B : FTIR (EP, BP) |
Matches with the standard pattern (dry the substance at 105 ±2°C for 2h) |
| Identification B: (IP) |
Gives reaction A of citrates |
| Identification C (EP, BP) |
A red colour develops |
| Identification C (IP) |
10% w/v solution is strongly acidic |
| Identification D (EP, BP) |
A white precipitate is formed. |
| Identification E: Water (EP, BP) |
<= 1.00% |
| Appearance of solution (EP, BP) |
20% solution in water is clear and colourless or not more intensely coloured than reference solution Y7, BY7 or GY7 |
| Appearance of solution (IP) |
20% solution in water is clear not more intensely coloured than reference solution YS7, BYS7 or GYS7 |
| Clarity of solution (USP) |
The sample solution shows the same clarity as that of water or its opalescence is not more pronounced than standard suspension A |
| Colour of solution (USP) |
Complies |
| Clarity and color of solution (JP) |
The solution is clear and colorless or has no more color than the control solutions (1), (2) or (3). |
| Melting point (BP, EP, USP) |
~153°C with dec. |
| Readily carbonisable substances (IP) |
Any color produced is not more intense than that of mixture of 1.0 mL of CCS solution and 9 mL of FCS |
| Readily carbonisable substances (EP, BP) |
The solution is not more intensely coloured than a mixture of 1 mL of red primary solution and 9 mL of yellow primary solution |
| Readily carbonisable substances (USP) |
The colour of the acid is nor darker than that of a similar volume of matching fluid K |
| Readily carbonisable substances (JP) |
The solution is not more colored than the matching fluid. |
| Oxalic acid (EP, BP, USP, JP) |
<= 0.036% |
| Sulfates (JP, BP, EP, USP, IP) |
<= 0.015% |
| Heavy metals (JP, IP) |
<= 0.0010% |
| Arsenic (IP) |
<= 0.0001% |
| Barium (IP) |
Any opalescence produced is not more intense than that of a mixture of 5 mL of solution A and 5 mL of distilled water |
| Calcium (IP) |
<= 0.02% |
| Iron (IP) |
<= 0.0050% |
| Chloride (IP) |
<= 0.0050% |
| Oxalic acid (IP) |
Any pink colour produced is not more intense than that produced by carrying out the test using 0.2 mg oxalic acid dissolved in 4 mL of water |
| Water (EP, BP, USP, JP, IP) |
<= 1.00% |
| Sulfated ash (EP, BP, IP) |
<= 0.10% |
| Residue on ignition (JP, USP) |
<= 0.10% |
| Assay (NaOH Titration, on anhydrous basis) : (IP) |
99.00-101.00% |
| Assay (NaOH Titration, on anhydrous basis) : (USP, EP, BP, JP) |
99.50-100.50% |
Storage and Shelf Life
| Storage |
Store below 30°C away from bright light. |
| Shelf life |
48 months. |
| Usage Recommendation |
Use before expiry date given on the product label. |
CAS Number :
77-92-9
Molecular Formula :
C₆H₈O₇
More Information
| Product Name |
Citric acid anhydrous |
| SKU |
TC105M |
| CAS No |
77-92-9 |
| EC No. |
201-069-1 |
| Molecular formula |
C₆H₈O₇ |