This kit is based on the solubility difference between HbS and HbA in Solubility Test Reagent.
When red cells are introduced into such a solution, they lyse immediately. The hemoglobin
released from the lysed red cells, is reduced by Reagent Mix provided with the kit. This reaction
causes precipitation of HbS leading to turbidity of the reaction mixture. However, HbA, as well
as other hemoglobins are soluble leading to clarity in the reaction mixture.
Technical Data Sheet (TD)
Hi-Super Speed Sickle Kit (Solubility Test for detection of Hemoglobin ‘S’)
Safety Data Sheet (SDS)
Hi-Super Speed Sickle Kit (Solubility Test for detection of Hemoglobin ‘S’)
Electronic Instructions for Use (eIFU)
Hi-Super Speed Sickle Kit (Solubility Test for detection of Hemoglobin ‘S’)
Hi-Super Speed Sickle Kit (Solubility Test for detection of Hemoglobin ‘S’)
Human hemoglobin is formed from two pairs of globin chains each with a heme group attached.
The binding of a heme group into the heme pocket in each chain is vital for the oxygen? carrying
capacity of the molecule and stabilizes the whole molecule. Alterations in the structure of
hemoglobin are usually brought about by point mutations that affect the coding for amino acids
in the globin chainsThis kit is based on the solubility difference between HbS and HbA in Solubility Test Reagent. When red cells are introduced into such a solution, they lyse immediately. The hemoglobin
released from the lysed red cells, is reduced by Reagent Mix provided with the kit. This reaction
causes precipitation of HbS leading to turbidity of the reaction mixture. However, HbA, as well
as other hemoglobins are soluble leading to clarity in the reaction mixture.