Thimerosol

SKU:
TC470M
CAS Number : 54-64-8
Molecular Formula : C₉H₉HgNaO₂S
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Product Details

Product Code TC470M
Molecular weight 404.81
Molecular formula C9H9HgNaO2S
CAS No. 54-64-8

Quality Control

Appearance (USP) White to light cream-colored, crystalline powder
Appearance (EP, BP) White or almost white, crystalline powder
Appearance (IP) White to light cream, crystalline powder
Solubility (USP) Freely soluble in water, soluble in alcohol, practically insoluble in ether
Solubility (EP, BP) Freely soluble in water, sparingly soluble or soluble in ethanol (96%), practically insoluble in methylene chloride
Solubility (IP) Freely soluble in water and in ethanol (95%), practically insoluble in ether
pH (0.8% in water) : (EP, BP) 6.00 - 8.00
pH (1% in water) : (IP) 6.00 - 8.00
pH (1% in water) : (USP) ~6.70
Appearance of solution (EP, BP) 8% solution in water is not more opalescent than reference suspension II and not more intensely coloured than reference solution B6
Identification A, melting range: (EP,BP) 103 - 115°C
Identification A, FTIR : (USP) Matches with the standard pattern
Identification A : (IP) Pale yellow precipitate is produced
Identification B : (USP) A pale yellow precipitate is formed
Identification B, FTIR : (EP, BP) Matches with the standard pattern
Identification B : (IP) Passes
Identification C : (USP) The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay
Identification C : (EP, BP) Passes
Identification D : (EP, BP) 8% solution in water gives reaction (a) of sodium
Mercury ions, UV : (USP) <= 0.70%
Ether-soluble matter : (IP) Weight of residue not more than 3 mg
Inorganic mercury compounds (EP, BP, IP) <= 0.70%
Loss on drying: (USP, IP, EP, BP) <= 0.50% (dry to constant weight under vacuum over phosphorus pentoxide, pressure not exceeding 0.7 kPa for 24 h)
Organic impurities, system suitability : resolution (USP) min. 3.5 between the thimerosal and thimerosal related compound A peaks
Organic impurities, system suitability : RSD (USP) <= 3.00%
Organic impurities, thiosalicylic acid : RSD (USP) <= 0.10%
Organic impurities, thimerosal related compound A : RSD (USP) <= 0.10%
Organic impurities, any other individual unspecified impurity : (USP) <= 0.10%
Organic impurities, total impurities : (USP) <= 1.00%
Assay, system suitability : resolution (USP) min. 3.5 between the thimerosal and thimerosal related compound A peaks
Assay, system suitability : RSD (USP) <= 0.73%
Assay (HPLC, on dried basis) : (USP) 97.00 - 102.00%
Assay (NH4SCN Titration, on dried basis) : (IP, EP, BP) 97.00 - 101.00%

Storage and Shelf Life

Storage Condition Store below 30°C away from bright light.
Shelf life 48 months.
CAS Number : 54-64-8
Molecular Formula : C₉H₉HgNaO₂S
More Information
Product Name Thimerosol
SKU TC470M
CAS No 54-64-8
EC No. 200-210-4
Molecular formula C₉H₉HgNaO₂S
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