Plot No. C40, Road No. 21Y, MIDC, Wagle Industrial Estate, Thane(W)-400604, MH, India
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L-Tyrosine
SKU:
TC122M
CAS Number :
60-18-4
Molecular Formula :
C₉H₁₁NO₃
Availability: In stock
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As low as
$67.10
Product Description
| Molecular weight | 181.19 |
|---|---|
| Molecular formula | C9H11NO3 |
| CAS No. | 60-18-4 |
Quality Control
| Appearance (USP) | White, crystals or crystalline powder |
|---|---|
| Appearance (JP) | White crystals or a crystalline powder |
| Appearance (EP, BP) | White or almost white, crystalline powder or colourless crystals |
| Solubility (USP) | Very slightly soluble in water, insoluble in alcohol and in ether |
| Solubility (EP, BP) | Very slightly soluble in water, practically insoluble in ethanol (96%). It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides |
| Solubility (JP) | Freely soluble in formic acid, and practically insoluble in water and in ethanol (99.5%). It dissolves in dilute hydrochloric acid and in ammonia TS |
| Identification A : FTIR (USP) | Matches with the standard pattern |
| Identification 1 : UV (JP) | Both spectra exhibit similar intensities of absorption at the same wavelengths |
| Identification A : Specific rotation (EP, BP) | -12.30 to -11.00° (c = 5% in 1:1 mixture of dilute hydrochloric acid R and water at 20 ± 0.5°C, dried substance) |
| Identification B : FTIR (EP, BP) | Matches with the standard pattern |
| Identification 2 : FTIR (JP) | Both spectra exhibit similar intensities of absorption at the same wave numbers |
| Identification C : TLC (EP, BP) | The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution |
| Identification D (EP, BP) | A dark red colour is produced within 15 min. |
| Identification E (EP, BP) | An orange-red colour is produced |
| Appearance of solution (EP, BP) | 2.5% solution in dilute hydrochloric acid R is clear and not more intensely coloured than reference solution Y7 |
| Clarity and color of solution (JP) | 5% warm solution in in 1M hydrochloric acid is clear and colorless |
| Optical rotation (JP) | -12.50° to -10.50° (c= 5% in 1M hydrochloric acid at 20° C, after drying) |
| Specific rotation (EP, BP) | -12.30 to -11.00° (c = 5% in 1:1 mixture of dilute hydrochloric acid R and water at 20 ± 0.5°C, dried substance) |
| Optical rotation (USP) | -11.20 to -9.80° (c = 5% in 1N hydrochloric acid at 25°C) |
| Residue on ignition (USP) | <= 0.40% |
| Residue on ignition (JP) | <= 0.10% |
| Sulfated ash (EP, BP) | <= 0.10% |
| Chloride (USP) | <= 0.04% |
| Chloride (JP) | <= 0.021% |
| Chloride (EP, BP) | <= 0.02% |
| Sulfate (USP) | <= 0.04% |
| Sulfate (JP) | <= 0.028% |
| Sulfate (EP, BP) | <= 0.03% |
| Ammonium (JP) | <= 0.02% |
| Iron (USP) | <= 0.0030% |
| Iron (JP, EP, BP) | <= 0.0010% |
| Heavy metals (JP) | <= 0.0010% |
| Loss on drying (USP, JP) | <= 0.30% (at 105°C, 3 hr) |
| Loss on drying (EP, BP) | <= 0.50% (at 105°C till constant weight) |
| Related compounds, system suitability : TLC (USP) | The chromatogram of the system suitability solution exhibits two clearly separated spots |
| Related compounds, any individual impurity : TLC (USP) | <= 0.50% |
| Related compounds, total impurities : TLC (USP) | <= 2.00% |
| Related substances: TLC (JP) | The spot other than the principal spot obtained from the sample solutiois not more intense than the spot obtained from the standard solution. |
| Ninhydrin-positive substances 1, system suitability (Amino acid analysis) : Resolution (EP, BP) | min. 1.5 between the peaks due to isoleucine and leucine |
| Ninhydrin-positive substances 2, impurity A at 570 nm (Amino acid analysis) : (EP, BP) | <= 0.50% |
| Ninhydrin-positive substances 3, any ninhydrin-positive substance, for each impurity (Amino acid analysis): (EP, BP) | <= 0.20% |
| Ninhydrin-positive substances 4, total impurity (Amino acid analysis) : (EP, BP) | <= 0.60% |
| Ammonium (Amino acid analysis) : (EP, BP) | <= 0.02 |
| Assay (NT, on dried basis) : (USP) | 98.50 - 101.50% |
| Assay (NT, dried substance) : (JP, EP, BP) | 99.00 - 101.00% |
Storage and Shelf Life
| Storage condition | Store below 30°C away from bright light. |
|---|---|
| Shelf life | 48 months. |
| Usage note | Use before expiry date given on the product label. |
CAS Number :
60-18-4
Molecular Formula :
C₉H₁₁NO₃
| Product Name | L-Tyrosine |
|---|---|
| SKU | TC122M |
| CAS No | 60-18-4 |
| EC No. | 200-460-4 |
| Molecular formula | C₉H₁₁NO₃ |
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