Plot No. C40, Road No. 21Y, MIDC, Wagle Industrial Estate, Thane(W)-400604, MH, India
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L-Threonine
SKU:
TC120M
CAS Number :
72-19-5
Molecular Formula :
C₄H₉NO₃
Availability: In stock
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As low as
$103.20
Product Identifier
| Product Code | TC120M |
|---|---|
| Molecular weight | 119.12 |
| Molecular formula | C4H9NO3 |
| CAS No. | 72-19-5 |
Technical Specification
| Appearance (USP) | White crystals |
|---|---|
| Appearance (JP) | White crystals or a crystalline powder |
| Appearance (EP, BP) | White or almost white, crystalline powder or colourless crystals |
| Solubility (USP) | Freely soluble in water; insoluble in absolute alcohol, in ether, and in chloroform |
| Solubility (EP, BP) | Soluble in water, practically insoluble in ethanol (96%) |
| Solubility (JP) | Freely soluble in formic acid, soluble in water, and practically insoluble in ethanol (95%) |
| Identification A : FTIR (USP) | Matches with the standard pattern |
| Identification A : Specific optical rotation (EP, BP) | -29.00° to -27.60° (c = 6% in water at 20 ± 0.5°C, dried substance) |
| Identification : FTIR (JP) | Matches with the standard pattern |
| Identification B : FTIR (EP, BP) | Matches with the standard pattern |
| Identification C : TLC (EP, BP) | The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution |
| Identification D (EP, BP) | A blue colour develops that changes to yellow after a few minutes |
| Appearance of solution (EP, BP) | 2.5% in water is clear and colourless |
| Clarity and color of solution (JP) | 5% solution in water is clear and colourless |
| pH (5% in water at 25°C) : (USP) | 5.00 -6.50 |
| pH (2.5% in water at 25°C) : (EP, BP) | 5.00 -6.50 |
| pH (1% in water at 25°C) : (JP) | 5.20 - 6.20 |
| Specific rotation (USP) | -29.10° to -26.70° (c = 6% in water at 25°C) |
| Specific rotation (EP, BP) | -29.00° to -27.60° (c = 6% in water at 20 ± 0.5°C, dried substance) |
| Specific rotation (JP) | -29.00° to -26.00° (c = 6% in water at 20°C, after drying) |
| Chloride (USP) | <= 0.05% |
| Chloride (JP) | <= 0.021% |
| Chloride (EP, BP) | <= 0.02% |
| Sulfate (USP) | <= 0.03% |
| Sulfate (EP, BP) | <= 0.03% |
| Sulfate (JP) | <= 0.028% |
| Iron (USP) | <= 0.003% |
| Iron (EP, BP) | <= 0.0010% |
| Heavy metals (JP) | <= 0.0020% |
| Ammonium (JP) | <= 0.020% |
| Arsenic (JP) | <= 0.00020% |
| Loss on drying (USP, JP) | <= 0.20% (at 105°C, 3 hr) |
| Loss on drying (EP, BP) | <= 0.50% (at 105°C, 2 hr) |
| Sulfated ash (EP, BP) | <= 0.10% |
| Residue on ignition (USP) | <= 0.40% |
| Residue on ignition (JP) | <= 0.10% |
| Related compounds, System suitability requirements : TLC (USP) | The chromatogram of the system suitability solution exhibits two clearly separated spots |
| Related compounds, acceptance criteria: TLC (USP) | Any secondary spot of the sample solution is not larger or more intense than the principal spot of the standard solution |
| Related compounds, individual impurity : TLC (USP) | <= 0.50% |
| Related compounds, Total impurities : TLC (USP) | <= 2.00% |
| Related substances : TLC (JP) | The spot other than the principal spot obtained from the sample solution is not more intense than the spot obtained from the standard solution. |
| Ninhydrin-positive substances, system suitability: Resolution, Amino acid analysis (EP, BP) | min. 1.5 between the peaks due to impurity D and leucine |
| Any ninhydrin-positive substances, for each impurity, Amino acid analysis (EP, BP) | <= 0.20% |
| Any ninhydrin-positive substances, total impurity, Amino acid analysis (EP, BP) | <= 0.50% |
| Ammonium, Amino acid analysis : (EP, BP) | <= 0.020% (at 570 nm) |
| Assay (NT, dried basis) : (USP) | 98.50 - 101.50% |
| Assay (NT, dried substance) : (EP, BP) | 99.00 - 101.00% |
| Assay (NT, dried substance) : (JP) | min. 98.50% |
Storage and Shelf Life
| Storage | Store below 30°C. |
|---|---|
| Shelf life | 48 months. |
| Use before expiry date | Use before expiry date given on the product label. |
CAS Number :
72-19-5
Molecular Formula :
C₄H₉NO₃
| Product Name | L-Threonine |
|---|---|
| SKU | TC120M |
| CAS No | 72-19-5 |
| EC No. | 200-774-1 |
| Molecular formula | C₄H₉NO₃ |
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