Plot No. C40, Road No. 21Y, MIDC, Wagle Industrial Estate, Thane(W)-400604, MH, India
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L-Cysteine hydrochloride monohydrate
SKU:
TC058M
CAS Number :
7048-04-6
Molecular Formula :
C₃H₇NO₂S.HCl.H₂O
Availability: In stock
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Product Description
| Molecular weight | 175.63 |
|---|---|
| Molecular formula | C3H7NO2S.HCl.H2O |
| CAS No. | 7048-04-6 |
Quality Control
| Appearance (USP, JP) | White crystals or crystalline powder |
|---|---|
| Appearance (EP, BP) | A white or almost white, crystalline powder or colourless crystals |
| Solubility (USP) | Soluble in water, in alcohol, and in acetone |
| Solubility (JP) | Very soluble in water, and soluble in ethanol (99.5%). It dissolves in 6 mol/L hydrochloric acid TS |
| Solubility (EP, BP) | Freely soluble in water, slightly soluble in ethanol (96%) |
| Identification A : FTIR (USP) | Matches with the standard pattern |
| Identification A : Specific optical rotation (EP, BP) | +5.50° to +7.00° (c= 8% in hydrochloric acid R1 at 25°C, dried substance) |
| Identification 1 : FTIR (JP) | Both spectra exhibit similar intensities of absorption at the same wave numbers |
| Identification 2 : Chloride (JP) | 10 mL of 2% solution and 1 mL of hydrogen peroxide responds to the qualitative test for chloride |
| Identification B : FTIR (EP, BP) | Matches with the standard pattern |
| Clarity and color of solution : (JP) | 10% solution in water is clear and colorless 10% solution in water is clear and colorless |
| Identification C : TLC (EP, ВР) | The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution |
| Identification D : (EP, BP) | The solution becomes green |
| Identification E: (EP, BP) | The solution gives reaction (a) of chlorides |
| pH (1% in water at 25°C) : (JP) | 1.30-2.30 |
| Appearance of solution (EP, ВР) | 2.5% solution in water is not more intensely coloured than reference solution BY6 |
| Clarity and color of solution : (JP) | 10% solution in water is clear and colorless 10% solution in water is clear and colorless |
| Optical rotation : (JP) | +6.00° to + 7.50° (c= 8% in 6M hydrochloric acid at 20°C, dried bais) |
| Optical rotation : (USP) | +5.70° to +6.80° (c = 8% in 6N hydrochloric acid, 25°C) |
| Specific optical rotation : (EP, BP) | +5.50° to +7.00° (c = 8% in hydrochloric acid R1, 20 ± 0.5°C) |
| Sulfate : (JP) | <= 0.021% |
| Sulfate: (USP, EP, BP) | <= 0.03% |
| Heavy metals : (JP) | <= 0.0010% |
| Iron (JP) | <= 0.0010% |
| Iron (USP) | <= 0.0030% |
| Iron (EP, BP) | <= 0.0020% |
| Loss on drying (JP) | 8.50 - 12.00% (in vacuum on phosphorus (V) oxide, 20 hours) |
| Loss on drying (USP) | 8.00 - 12.00% (dry at room temperature in vacuum at pressure NMT 5 mm of mercury, 24 hr) |
| Loss on drying (EP, BP) | 8.00 - 12.00% (at a pressure NMT 0.7kPa gor 24 hr) |
| Residue on ignition: (JP) | <= 0.10% |
| Residue on ignition : (USP) | <= 0.40% |
| Sulfated ash (EP, BP) | <= 0.10% |
| Ammonium (Amino acid analysis) : (EP, BP) | <= 0.02% |
| Ammonium (JP) | <= 0.02% |
| Related compounds, System suitability : TLC (USP) | The chromatogram of the system suitability solution exibits two clearly separated spots |
| Related compounds, TLC : (USP) | Any secondary spot of the sample solution is not larger or more intense than the principal spot of the standard solution |
| Related substances, TLC : (JP) | The spot other than the principal spot obtained with the sample solution is not more intense than the spot obtained with the standard solution. |
| Related compounds, Individual impurities, TLC : (USP) | <= 0.5% |
| Related compounds, Total impurities, TLC : (USP) | <= 2.0% |
| Ninhydrin-positive substances, system sutem suitability (Amino acid analysis) : Rsolution (EP, BP) | >=1.50 between the peaks due to isoleucine and leucine |
| Ninhydrin-positive substances 1 (Amino acid analysis) : Impurity A (EP, BP) | <= 0.50% |
| Ninhydrin-positive substances 2 (Amino acid analysis) : Any ninhydrin-positive substance for each impurity (EP, BP) | <= 0.20% |
| Ninhydrin-positive substances 3 (Amino acid analysis) : Total impurity (EP, BP) | <= 1.00% |
| Assay (Iodometry, dried substance) : (EP, BP, JP) | 98.50 - 101.00% |
| Assay (Iodometry, dried basis) : (USP) | 98.50 - 101.50% |
Storage and Shelf Life
| Storage | Store below 30°C away from bright light. |
|---|---|
| Shelf life | 48 months |
CAS Number :
7048-04-6
Molecular Formula :
C₃H₇NO₂S.HCl.H₂O
| Product Name | L-Cysteine hydrochloride monohydrate |
|---|---|
| SKU | TC058M |
| CAS No | 7048-04-6 |
| EC No. | 200-157-7 |
| Molecular formula | C₃H₇NO₂S.HCl.H₂O |
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