L-Histidine is also a precursor to histamine, a vital inflammatory agent in immune responses.It binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes.
Histidine is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group, a carboxylic acid group, and an imidazole side chain, classifying it as a positively charged amino acid at physiological pH