Complete Supplement Mixture w/o ADE is used as a dropout supplement for all strains of Saccharomyces cerevisiae. Complete Supplement Mixture (CSM) is composed of all
the amino acids except Adenine required for the vigorous growth of Saccharomyces cerevisiae. It can be mixed with yeast nitrogen base (YNB), ammonium sulphate and an appropriate carbon source (glucose/galactose/raffinose) to produce a media suitable for the growth of adenine prototrophs but not adenine auxotrophs