HiOsteoXL™ Osteocyte Differentiation Medium w/ L-Glutamine and Sodium bicarbonate

HiOsteoXLTM Osteocyte Differentiation Medium is optimized for osteogenic differentiation of actively proliferating human mesenchymal stem cells in vitro. Clonally expanded mesenchymal stem cells (MSCs) have ability to differentiate into three types of cells - adipocytes, chondrocytes and osteocytes. Differential potential of MSCs in these three cell types is considered as a reliable functional criterion to identify MSCs and distinguish them from preadipocytes, prechondrocytes and preosteocytes, each of which gives rise to only one cell type. Osteogenesis in vitro follows a highly ordered and well characterized temporal sequence. AL522 is HiOsteoXLTM Osteocyte Differentiation Medium consisting of two parts - Part A: HiOsteoXLTM Basal Medium It is a basal medium containing organic and inorganic salts, amino acids, vitamins and sodium bicarbonate. It is devoid of antibiotics and antimycotics. Part B: HiOsteoXLTM Osteogenic Differentiation Supplement It is a proprietary supplement formulated to contain induction factors that induce osteogenic differentiation of human mesenchymal stem cells. HiOsteoXLTM Osteogenic Differentiation Medium contains phenol red. Use of phenol red containing medium may enhance and accelerate rate of calcium deposition during osteogenic differentiation.