Tigecycline

HiComb™ MIC Strip, Modified is made up of inert material with 15 extensions that carry porous material at the edges, resembling tooth of comb. It covers 15 two-fold dilutions in a single strip having highest concentration at the top and lowest concentration at the bottom. Towards the stem of the strip, MIC reading scale in mcg/ml is given along with the HiMedia reference code. A defined concentration of Tigecycline is loaded on each of the edges carrying porous material, so as to create gradient when placed on agar plate. When applied to the agar surface, the antibiotic instantaneously diffuses into the surrounding medium in high to low amounts from one end of the strip to the other. The gradient remains stable after diffusion, and the zone of inhibition created takes the form of ellipse