Lateral Flow and Nanotechnology

The lateral flow immunoassay test, also known as immunochromatography assay or rapid point of care test is an extremely versatile and fast method for visual detection of presence or absence of target analyte in a sample. Noble metal nanoparticles like gold can be utilized due to their optical properties with which visual detection by naked eye can be achieved with excellent sensitivity. Lateral flow tests are low cost, simple, rapid, portable, usually show results within 5-20 minutes. Hence these tests are used for as point of care testing in various sectors like biomedicine, agriculture, food and environmental sciences.

HiMedia provides monodispersed; citrate stabilized gold and silver nanoparticles with uniform shape and narrow size distribution. These gold and silver nanoparticles have excellent biocompatibility, stability and can be easily functionalized with biological molecules like proteins, drugs, antibodies, enzymes, nucleic acids (DNA or RNA), and fluorescent dyes on their surface, for diverse medical applications and biological activities.

HiMedia offers comprehensive range of buffers extensively used in molecular biology, biochemistry and biotechnology applications. These buffers can be used in optimizations steps of immunoassays viz., dilution of sample/ antigen/antibodies, coating, washing, blocking.

HiMedia is delivering a range of chemicals and reagents for use in the development of diagnostic lateral flow immunoassays. These chemicals and reagents have been tested for their physical, chemical and functional characteristics to improve the reliability of results.