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Neomycin sulfate salt, Cell Culture Tested
SKU:
TC031
CAS Number :
1405-10-3
Synonym :
Framycetin, Neomycin B, Soframycin, Mycifradin
Molecular Formula :
C₂₃H₄₆N₆O₁₃·3H₂SO₄
Availability: In stock
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$21.60
Product Identifier
| Product Code | TC031 |
|---|---|
| Molecular Weight | 908.88 |
| Molecular Formula | C₂₃H₄₆N₆O₁₃.₃H₂SO₄ |
| CAS No | 1405-10-3 |
| Synonym | Framycetin, Neomycin B, Soframycin, Mycifradin |
Technical Specification
| Description | Neomycin sulfate salt is an aminoglycoside antibiotic obtained from Streptomyces fradie. It is composed of three separate compounds - neomycin A, neomycin B (framycetin), and neomycin C. Neomycin irreversibly binds to specific 30S-subunit proteins and this interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This type of interaction interferes with initiation complex, causes misreading of mRNA and incorrect insertion of amino acids into the polypeptide. These events lead to non-functional or toxic peptides and breakdown of polysomes into non-functional monosomes. It is a broad spectrum antibiotic active against Gram-positive and Gram-negative organisms. It also prevents growth of protozoa, algae, and mammalian cells. In cell culture, Neomycin sulfate is used as an anti-microbial agent to prevent contamination. |
|---|---|
| Appearance | White to yellow hygroscopic crystals or powder. |
| Solubility | 100 mg soluble in 1 ml of water. |
| pH (1% in water at 25°C) | 5.00 -7.50 |
| Specific rotation | (+)53.50° to (+)59.00° (C = 10% in water at 25°C) |
| FTIR | Matches with the standard pattern |
| Antibiotic Sensitivity | Passes |
| Potency | NLT 680 µg/mg |
| Cell Culture Test | Passes |
| Storage | Store below 30°C away from bright light. |
| Shelf life | 36 months. |
CAS Number :
1405-10-3
Synonym :
Framycetin, Neomycin B, Soframycin, Mycifradin
Molecular Formula :
C₂₃H₄₆N₆O₁₃·3H₂SO₄
| Product Name | Neomycin sulfate salt, Cell Culture Tested |
|---|---|
| SKU | TC031 |
| CAS No | 1405-10-3 |
| Molecular formula | C₂₃H₄₆N₆O₁₃·3H₂SO₄ |
| Molecular Weight | 908.88 |
| Synonym | Framycetin, Neomycin B, Soframycin, Mycifradin |
| Storage | Store below 30°C away from bright light. |
| Shelf Life | 3 Years |
| Appearance | White to yellow hygroscopic crystals or powder |
|---|---|
| Solubility | 100 mg soluble in 1 ml of water |
| pH (1% in water at 25°C) | 5.00 - 7.50 |
| Specific Rotation | (+53.50°) to (+59.00°) (C = 10% in water at 25°C) |
| FTIR | Matches with the standard pattern |
| Antibiotic Sensitivity | Passes |
| Potency | NLT 680 μg/mg |
| Cell Culture Test | Passes |
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